ADEMPAS (riociguat)
SELF ADMINISTRATION - ORAL
Indications for Prior Authorization:
- Indicated in adults for the treatment of pulmonary arterial hypertension (PAH) [WHO group 1] to improve exercise capacity, WHO functional class and to delay clinical worsening.
- Also indicated in the adults for the treatment of persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH) [WHO group 4] after surgical treatment, or inoperable CTEPH, to improve exercise capacity and WHO functional class.
Patients must meet the following criteria for the indication(s) above:
- Patient is 18 years of age or older, AND
- Diagnosis of PAH or CTEPH confirmed by chart note documentation, AND
- Prescribed by or in consultation with a cardiologist or pulmonologist, AND
- Patient has had a right heart catheterization confirmed by chart note documentation, OR
- Results of the right heart catheterization confirms diagnosis of WHO group 1 PAH
- For CTEPH: disease is persistent/inoperable
Dosing:
- 1 mg by mouth 3 times daily
- For oral use only
- Dose does not exceed 7.5 mg per day
Approval:
- 1 year
Last review date: February 24, 2020