Hemangeol (propranolol hydrochloride oral solution) - PA, NF

Indications for Prior Authorization

Hemangeol (propranolol hydrochloride oral solution)
  • For diagnosis of Infantile hemangioma
    Indicated for the treatment of proliferating infantile hemangioma requiring systemic therapy.

Criteria

Hemangeol

Prior Authorization (Initial Authorization)

Length of Approval: 6 Month(s) [A]

  • Diagnosis of proliferating infantile hemangioma
  • AND
  • Patient is less than or equal to 12 months of age [A]
  • AND
  • One of the following:
    • Trial or intolerance to generic propranolol oral solution
    • OR
    • Provider attestation that there is potential for an allergic reaction due to a non-active ingredient that is contained in generic propranolol oral solution but not included in the requested product
Hemangeol

Prior Authorization (Reauthorization)

Length of Approval: 12 Month(s)

  • Patient demonstrates positive clinical response to therapy (e.g., reduction in size, absence of functional impact, tissue softening)
  • AND
  • Patient is less than or equal to 18 months of age [A]
  • AND
  • One of the following:
    • Trial or intolerance to generic propranolol oral solution
    • OR
    • Provider attestation that there is potential for an allergic reaction due to a non-active ingredient that is contained in generic propranolol oral solution but not included in the requested product
Hemangeol

Non Formulary (Initial Authorization)

Length of Approval: 6 Month(s) [A]

  • Submission of medical records (e.g., chart notes) confirming diagnosis of proliferating infantile hemangioma
  • AND
  • Patient is less than or equal to 12 months of age [A]
  • AND
  • Submission of medical records (e.g., chart notes) confirming one of the following:
    • Trial or intolerance to generic propranolol oral solution
    • OR
    • There is potential for an allergic reaction due to a non-active ingredient that is contained in generic propranolol oral solution but not included in the requested product
Hemangeol

Non Formulary (Reauthorization)

Length of Approval: 12 Month(s)

  • Patient demonstrates positive clinical response to therapy (e.g., reduction in size, absence of functional impact, tissue softening)
  • AND
  • Patient is less than or equal to 18 months of age [A]
  • AND
  • Submission of medical records (e.g., chart notes) confirming one of the following:
    • Trial or intolerance to generic propranolol oral solution
    • OR
    • There is potential for an allergic reaction due to a non-active ingredient that is contained in generic propranolol oral solution but not included in the requested product
P & T Revisions

2026-08-10, 2026-07-08, 2026-06-03, 2026-01-08, 2024-12-23, 2024-01-04

  1. Hemangeol Prescribing Information. Pierre Fabre Pharmaceuticals, Inc. Parsippany, NJ. June 2021.
  2. Krowchuk DP, Frieden IJ, Mancini AJ, et al. Clinical Practice Guideline for the Management of Infantile Hemangiomas. Pediatrics. 2018;143(1):e20183475.

  1. Treatment typically is continued for at least 6 months and often is maintained until 12 months of age (occasionally longer). [2]

  • 2026-08-10: Addition of NF criteria
  • 2026-07-08: Addition of NF criteria
  • 2026-06-03: Addition of trial requirement
  • 2026-01-08: 2026 Annual Review. No criteria changes.
  • 2024-12-23: 2025 Annual Review - no criteria changes
  • 2024-01-04: New Program