Phosphate Binders
Indications for Prior Authorization
Fosrenol (lanthanum carbonate)
-
For diagnosis of Hyperphosphatemia
Indicated to reduce serum phosphate in patients with end-stage renal disease (ESRD).
Velphoro (sucroferric oxyhydroxide)
-
For diagnosis of Hyperphosphatemia
Indicated for the control of serum phosphorus levels in adult and pediatric patients 9 years of age and older with chronic kidney disease on dialysis.
Criteria
Velphoro
For state-mandated plans in Illinois or other states where applicable: Step therapy requirements do NOT apply. Beginning January 1, 2026, step therapy requirements or use of the authorization of alternative covered medications in a manner that effectively creates a step therapy requirement will not be imposed.
Step Therapy
Length of Approval: 12 Month(s)
- Both of the following:
- Diagnosis of hyperphosphatemia in chronic kidney disease on dialysis AND
- One of the following:
- Trial and failure of a minimum 30-day supply, contraindication, or intolerance to two of the following:
- calcium carbonate
- calcium acetate
- sevelamer carbonate
- sevelamer HCl
- Auryxia
- Patient is younger than or equal to 12 years of age
Brand Fosrenol
For state-mandated plans in Illinois or other states where applicable: Step therapy requirements do NOT apply. Beginning January 1, 2026, step therapy requirements or use of the authorization of alternative covered medications in a manner that effectively creates a step therapy requirement will not be imposed.
Step Therapy
Length of Approval: 12 Month(s)
- Requested drug is being used for a Food and Drug Administration (FDA)-approved indication AND
- Trial and failure of a minimum 30-day supply, contraindication, or intolerance to two of the following:
- calcium carbonate
- calcium acetate
- sevelamer carbonate
- sevelamer HCl
P & T Revisions
1970-01-01, 2025-12-18, 2025-12-02, 2024-08-26, 2024-05-18, 2023-05-24, 2022-05-31
References
- Velphoro Prescribing Information. Fresenius Medical Care North America. Waltham, MA. July 2024.
- Fosrenol Prescribing Information. Takeda Pharmaceutical Company Limited. Lexington, MA. May 2020.
Revision History
- 1970-01-01: No criteria changes
- 2025-12-18: no criteria changes, added IL statute operational note
- 2025-12-02: Removed Phoslyra as a target drug
- 2024-08-26: update guideline
- 2024-05-18: 2024 Annual Review
- 2023-05-24: 2023 Annual Review.
- 2022-05-31: New Program
HEALTHY LIVING