ELZONRIS (tagraxofusp)
MEDICAL BENEFIT - INTRAVENOUS ADMINISTRATION
Indications for Prior Authorization:
- Indicated in adults and pediatric patients ≥ 2 years of age for the treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN)
Patients must meet the following criteria for the indication(s) above:
- Patient is ≥ 2 years of age, AND
- Diagnosis of BPDCN confirmed by chart note documentation, AND
- Prescribed by or in consultation with an oncologist or hematologist
Dosing:
- IV: 12 mcg/kg over 15 minutes once daily on days 1 to 5 of a 21-day cycle
- Prior to first dose, ensure that the serum albumin level is ≥ 3.2 g/dL
- Dosing period may be extended for dose delays up to day 10 of the cycle
- Consider pre-treatment with histamine-1 antagonist, histamine-2 antagonist, a corticosteroid, and acetaminophen approximately 1 hour prior to administering Elzonris™
Approval:
- 1 year
Last review date: May 21, 2019