Plecanatide (Trulance)

SELF ADMINISTRATION - ORAL 

Indications for Prior Authorization:

  • Treatment of chronic idiopathic constipation (CIC) in adults

  • Treatment of irritable bowel syndrome with constipation (IBS-C) in adults

Patients must meet the following criteria for the indication(s) above:

Chronic idiopathic constipation (CIC)

  • Diagnosis of CIC
  • 18 years of age or older
  • Member has increased fiber intake and tried-failed a stimulant laxative or osmotic laxative
  • Member is not concomitantly taking Linzess or Amitiza

Irritable bowel syndrome with constipation (IBS-C)

  • Diagnosis of IBS-C
  • 18 years of age or older
  • Member has increased fiber intake and tried-failed an osmotic laxative
  • Member is not concomitantly taking Linzess or Amitiza

The following conditions do not meet the criteria for use as established by WHA P&T committee:

  • All non-FDA approved uses not listed in the approved indications

Dosing:

  • The recommended dosage is 3mg taken once daily

Approval:

  • 1 year

Last review date: April 22, 2019